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osteoporosis

The answers to questions such as -

What is osteoporosis?

Am I at risk?

Can I prevent osteoporosis?

What are the treatments for osteoporosis?

Osteoporosis

Osteoporosis literally means 'porous bones'.

The bones in our skeleton are made of a thick outer shell and a strong inner mesh filled with collagen (protein), calcium salts and other minerals. The inside looks like honeycomb, with blood vessels and bone marrow in the spaces between bone. Osteoporosis occurs when the holes between bone become bigger, making it fragile and liable to break easily. Osteoporosis usually affects the whole skeleton but it most commonly causes breaks (fractures) to bone in the wrist, spine and hip.

Bone is alive and constantly changing. Old, worn out bone is broken down by cells called osteoclasts and replaced by bone building cells, called osteoblasts. This process of renewal is called bone turnover.

Facts and figures

  One in two women and one in five men in the UK will suffer a fracture after the age of 50

  Every 3 minutes someone has a fracture due to osteoporosis

  An estimated 3 million people in the UK suffer from osteoporosis

  Each year there are more than 230,000 fractures which include over

          - 70,000 hip fractures

          - 50,000 wrist fractures

          - 120,000 spinal fractures

  Osteoporosis costs the NHS and government over £1.7 billion each year, that's £5 million each day!

Are you at risk?

We are all potentially at risk of osteoporosis because of the bone loss that occurs as we get older, particularly as we are living longer as a population, but there are also many other factors, which can increase your risk of osteoporosis:

For women:

  a lack of oestrogen, caused by

  early menopause (before age 45)

  early hysterectomy (before the age of 45), particularly when both ovaries are removed (oophorectomy)

  missing periods for six months or more (excluding pregnancy) as a result of over-exercising or over-dieting

For men:

  low levels of the male hormone, testosterone (hypogonadism)

 For men and women:

  long-term use of high dose corticosteroid tablets (for conditions such as arthritis and asthma)

  close family history of osteoporosis (mother or father), particularly if your mother suffered a hip fracture

  other medical conditions such as Cushing's syndrome and liver and thyroid problems

  malabsorption problems (coeliac disease, Crohn's disease, gastric surgery)

  long-term immobility

  heavy drinking

  smoking

If you think you may have one or more of these risk factors you are at increased risk of developing osteoporosis. You need to discuss your risk with your doctor and find out how to prevent and treat the disease. If you have broken a bone after a minor bump or fall you may already have osteoporosis and you should discuss this with your GP.

Do I have osteoporosis?

Because you cannot see of feel your bone getting thinner you will probably be quite unaware of any problems with your bone health. Osteoporosis is a silent disease and for most people, the first sign that something is wrong can be when they break a bone, often in the wrist or spine after a minor incident, although not all fractures are due to osteoporosis.

Can I be tested for osteoporosis?

A normal x-ray of bone cannot reliably measure bone density but is useful to identify spinal factures, explains back pain, height loss or kyphosis.

A bone density scan, called a dual energy x-ray absorptiometry (DXA) scan, is used to measure the density of bones and compare this to a normal range. This test is currently the most accurate and reliable means of assessing the strength of your bones and your risk or fracture.

Can I prevent osteoporosis?

Your genes determine the potential height and strength of your skeleton but lifestyle factors can influence the amount of bone you invest in your bone 'bank' during your youth and how much you save in later life.

Follow a 'Bone-Friendly' diet

Healthy bones need a well-balanced diet, incorporating minerals and vitamins from different food groups.
You especially need to ensure that your diet is rich in calcium. The best sources of calcium are milk and dairy products such as cheese and yogurt. Non-dairy sources of calcium include green leafy vegetables, baked beans, bony fish and dried fruit.

Click here to download our information leaflet on Calcium rich foods and bone health or order our booklet Diet and Bone Health for £3.

Take regular, weight-bearing exercise

Like muscles and other parts of the body, bones suffer if they are not used. They need regular weight-bearing exercise that exerts a loading impact and stretches and contracts the muscles, stimulating bone to strengthen. Good bone building exercises include running, skipping, aerobics, tennis, even brisk walking. Try to exercise at least three times a week for a minimum for 20 minutes. If you haven't exercised for a while, start gently and check with your doctor if you have another health problem and are worried about exercising.

What else can I do?

  • If you are a smoker - give up! Smoking has a toxic effect on bone in men and women. It can cause women to have an early menopause and may increase the risk of hip fracture in later life. Stopping smoking will benefit your bones and your general health and fitness.
  • Watch what you drink! Drinking too much alcohol is damaging to bone turnover. Limit your alcohol intake to a maximum of 21 units per week for men and 14 units for women.

There has been concern, as the result of some research studies, that a high vitamin A intake may increase the risk of broken bones. Studies suggest that a daily vitamin A intake greater than 1500 micrograms retinol equivalents (RE) (not far in excess of the reference nutrient intake [RNI] 700 micrograms/d RE for men; 600 micrograms/d RE for women) may be associated with lower bone mineral density and a higher risk of hip fracture. However not all studies have confirmed this link and further research is urgently required. Since excessive amounts of vitamin A might be attained from supplements containing retinol, older people might want to avoid higher doses of pure cod liver oil. (pure cod liver oil for instance could provide 1200 micrograms RE of vitamin A in a 10ml dose).

A government committee is examining this issue and any firm recommendations will be posted when they are available. Meanwhile if you are taking a number of dietary supplements it may be useful to calculate the total amount of vitamin A being consumed and avoid excessive amounts.

Note:
• Retinol –measured in retinol equivalents (RE) - is the type of Vit A that there is concern about .It occurs in fish and dairy products. Vit A as carotene in vegetables is not going to cause these potential problems
• Retinol may be expressed in IU (international units). 1000IU =300 micrograms

Treatments

For people who have been diagnosed with osteoporosis there are a range of treatments available. The most common treatments include:

Bisphosphonates are non hormonal drugs, which help maintain bone density and reduce fracture rates.

Calcium and vitamin D supplements can be of benefit for older people to reduce the risk of hip fracture.

Hormone replacement therapy (HRT) is oestrogen replacement for women at the menopause, which help maintain bone density and reduce fracture rates for the duration of therapy. For more information on the NOS' position on HRT click here.

Selective Estrogen Receptor Modulators (SERMs) are drugs which act in a similar way to oestrogen on the bone, helping to maintain bone density and reduce fracture rates specifically at the spine.

Testosterone therapy is testosterone placement for men with low testosterone levels to help maintain bone density.

 

 

Strong healthy bone

Osteoporotic bone